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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
19.09
Human Site:
S2137
Identified Species:
42
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2137
P
N
R
Q
G
T
G
S
L
S
E
S
S
I
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2562
R
S
Q
E
R
R
Q
P
S
S
S
S
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2134
P
N
R
Q
G
T
G
S
L
S
E
S
S
I
P
Dog
Lupus familis
XP_547425
2465
277756
S2279
P
N
R
Q
G
T
G
S
L
S
E
S
S
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S2097
P
N
R
Q
G
T
G
S
L
S
E
S
S
I
P
Rat
Rattus norvegicus
Q07652
2222
252098
S2046
P
N
R
Q
G
T
G
S
L
S
E
S
S
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
N2019
T
P
P
A
T
P
P
N
R
D
H
T
P
Y
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
A1662
G
D
T
I
E
M
D
A
M
K
E
S
I
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1684
S
Y
P
T
L
A
S
R
R
A
G
I
G
R
R
Honey Bee
Apis mellifera
NP_001159376
1904
215872
T1737
A
S
T
S
P
A
R
T
P
S
P
I
H
H
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1799
S
R
A
S
S
S
E
R
M
D
P
E
S
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
0
N.A.
13.3
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
33.3
N.A.
6.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
19
0
10
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
19
0
0
0
0
0
% D
% Glu:
0
0
0
10
10
0
10
0
0
0
55
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
46
0
46
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
19
10
46
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
46
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
19
0
0
0
0
0
0
% M
% Asn:
0
46
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
46
10
19
0
10
10
10
10
10
0
19
0
10
0
46
% P
% Gln:
0
0
10
46
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
10
10
46
0
10
10
10
19
19
0
0
0
0
10
10
% R
% Ser:
19
19
0
19
10
10
10
46
10
64
10
64
64
10
0
% S
% Thr:
10
0
19
10
10
46
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _